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A facile synthesis of 2-oxazolines using a PPh3–DDQ system
Authors:Quancai Xu  Zhengning Li  
Affiliation:aCollege of Environmental and Chemical Engineering, Dalian University, Dalian 116622, China;bLiaoning Key Laboratory of Bioorganic Chemistry, Dalian University, Dalian 116622, China
Abstract:A facile and efficient synthesis of 2-oxazolines from N-(2-hydroxyethyl)amides using a triphenylphosphine–2,3-dichloro-5,6-dicyanobenzoquinone (PPh3–DQQ) system is described. The reaction proceeds under neutral and mild conditions, and excellent yields are obtained.
Keywords:2-Oxazoline   Synthesis   DDQ   Triphenylphosphine
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