A facile synthesis of 2-oxazolines using a PPh3–DDQ system |
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Authors: | Quancai Xu Zhengning Li |
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Affiliation: | aCollege of Environmental and Chemical Engineering, Dalian University, Dalian 116622, China;bLiaoning Key Laboratory of Bioorganic Chemistry, Dalian University, Dalian 116622, China |
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Abstract: | A facile and efficient synthesis of 2-oxazolines from N-(2-hydroxyethyl)amides using a triphenylphosphine–2,3-dichloro-5,6-dicyanobenzoquinone (PPh3–DQQ) system is described. The reaction proceeds under neutral and mild conditions, and excellent yields are obtained. |
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Keywords: | 2-Oxazoline Synthesis DDQ Triphenylphosphine |
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