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MASIC: a software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features |
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| Authors: | Monroe Matthew E Shaw Jason L Daly Don S Adkins Joshua N Smith Richard D |
| Institution: | Pacific Northwest National Laboratory, Richland, WA 99354, USA. matthew.monroe@pnl.gov |
| Abstract: | Quantitative analysis of liquid chromatography (LC)-mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data is essential to many proteomics studies. We have developed MASIC(2) to accurately measure peptide abundances and LC elution times in LC-MS/MS analyses. This software program uses an efficient processing algorithm to quickly generate mass specific selected ion chromatograms from a dataset and provides an interactive browser that allows users to examine individual chromatograms with a variety of options. |
| Keywords: | Liquid chromatography– tandem mass spectrometry (LC– MS/MS) Quantitation Proteomics Quantification Selected ion chromatogram |
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