A new synthesis of a potent cancer chemopreventive agent, 13-oxo-15,16-dinorlabda-8(17),11E-dien-19-oic acid from trans-communic acid |
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| Authors: | Katoh Takahiro Tanaka Reiko Takeo Masatoshi Nishide Kiyoharu Node Manabu |
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| Affiliation: | Kyoto Pharmaceutical University, Yamashina, Japan. |
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| Abstract: | The first synthesis of a labdane diterpenoid, (-)-13-oxo-15,16-dinorlabda-8(17),11E-dien-19-oic acid [(-)-1a], isolated from the stem bark of Thuja standishii (GORD.) CARR., from the major component trans-communic acid (3a) is described. |
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