|
|||||
|
|
Concise synthesis of pochonin A, an HSP90 inhibitor |
|
| Authors: | Moulin Emilie Barluenga Sofia Winssinger Nicolas |
| Affiliation: | Institut de Science et Ingénierie Supramoleculaires, Université Louis Pasteur, 8 allée Gaspard Monge, 67000 Strasbourg, France. |
| Abstract: | [chemical reaction: see text]. An expedient synthesis of (-)-pochonin A is reported (seven steps). This natural product is closely related to radicicol and was shown to be a 90 nM inhibitor of HSP90. |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ | |