HPLC Determination of Ritodrine Hydrochloride in Pharmaceutical Formulations |
| |
Authors: | H. D. Revanasiddappa B. Manju |
| |
Affiliation: | (1) Department of Chemistry, University of Mysore, Manasagangotri, Mysore, 570 006 Karnataka, India;(2) Department of Chemistry, P.E.S. College of Engineering, Mandya, 571401, India |
| |
Abstract: | A simple, rapid, and accurate HPLC method is described for the determination of ritodrine hydrochloride (RTH) in both pure form and pharmaceutical formulations. A Hypersil Shendon ODS column with a mobile phase of dibasic phosphate buffer and acetonitrile (75 : 25) and isoxsuprine hydrochloride were used as an internal standard. The flow rate was 1 mL min–1 and the effluent was monitored at 270 nm pH 4.0. The calibration graph is linear in the range 2–30 g mL–1. The proposed HPLC method has been successfully employed for the determination of RTH in Yutopar tablets and injection solutions. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|