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Lyciumaside and Lyciumate: A New Diacylglycoside and Sesquiterpene Lactone from Lycium shawii |
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| Authors: | Najeeb Ur Rehman Hidayat Hussain Samia Ahmed Al‐Riyami René Csuk Mohammed Khiat Ghulam Abbas Ahmed Al‐Rawahi Ivan R. Green Ishtiaq Ahmed Ahmed Al‐Harrasi |
| Affiliation: | 1. UoN Chair of Oman's Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al Mauz, Nizwa, Sultanate of Oman;2. +96825446328+96825446612;3. Organische Chemie, Martin‐Luther Universit?t Halle‐Wittenberg, Halle;4. Department of Biological Sciences and Chemistry, University of Nizwa, Birkat Al Mauz, Nizwa, Sultanate of Oman;5. Department of Chemistry and Polymer Science, University of Stellenbosch, Matieland, South Africa;6. Karlsruhe Institute of Technology (KIT), DFG Centre for Functional Nanostructures, Karlsruhe |
| Abstract: | One new diacylglycoside named lyciumaside ( 1 ) and a new sesquiterpene lactone named lyciumate ( 2 ) were isolated from Lycium shawii Roem . & Schult . The structures of the two new compounds were elucidated based on 1D‐ (1H‐ and 13C‐NMR and NOE) and 2D‐NMR (COSY, HSQC, and HMBC) spectroscopic techniques, and mass spectrometry (ESI‐MS). Preliminary evaluations demonstrated lyciumaside ( 1 ) possesses strong antioxidant activity with an IC50 = 30 μg/ml (80% inhibition) while it was inactive in α‐glucosidase and urease enzymes assays. |
| Keywords: | Natural product Lycium shawii Diacylglycoside Sesquiterpene lactone Antioxidant activity |