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Synthesis of pregnane derivatives
Authors:E V Popova  V A Andryushina  G S Grinenko
Abstract:Pregnane derivatives have been obtained from the cyanohydrins of androst-4-en-3, 17-dione and of 3beta-acetoxyandrost-5-en-17-one. It has been shown that when both a nitrile group and an ethylenedioxy group are present in an androstane derivative a Grignard reaction in anisole takes place simultaneously at the two groups.S. Ordzhonikidze All-Union Scientific-Research Institute of Pharmaceutical Chemistry, Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 324–327, May–June, 1984.
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