Microwave assisted synthesis of N-arylheterocyclic substituted-4-aminoquinazoline derivatives |
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| Authors: | Liu Gang Yang Song Song Baoan Xue Wei Hu Deyu Jin Linhong Lu Ping |
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| Institution: | Center for Research and Development of Fine Chemicals, Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guiyang, 550025, P. R. China. |
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| Abstract: | A simple, efficient, and general method has been developed for the synthesis of various N-aryl heterocylic substituted-4-aminoquinazoline compounds from 4-chloro- quinazoline and aryl heterocyclic amines under microwave irradiation using 2-propanol as solvent. The advantages of the use of microwave irradiation in relation to the classical method were demonstrated. |
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