| 3-取代苯甲酰氨基-2-硫代-2,4-噻唑烷二酮类衍生物的新合成法 |
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| 引用本文： | 褚长虎,许鹏飞,惠新平,张自义,廖仁安,李之春.3-取代苯甲酰氨基-2-硫代-2,4-噻唑烷二酮类衍生物的新合成法[J].高等学校化学学报,2001,22(5):768-770. |
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| 作者姓名： | 褚长虎 许鹏飞 惠新平 张自义 廖仁安 李之春 |
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| 作者单位： | 1. 兰州大学化学化工学院, 应用有机化学国家重点实验室, 兰州 730000;
2. 南开大学元素有机化学国家重点实验室, 天津 300071 |
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| 摘 要： | 通过简便的路线合成了8个3-取代苯甲酰氨基-2-硫代-2,4-噻唑烷二酮衍生物,并对其反应机理进行了讨论.所有化合物的结构均经元素分析、1HNMR、IR和MS谱确认.初步的生物活性测试结果表明,代表化合物表现出良好的抗菌活性和植物生长调节活性.
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| 关 键 词： | 2-硫代-2 4-噻唑烷二酮 合成 机理 生物活性 |
| 文章编号： | 0251-0790（2001）05-0768-03 |
| 收稿时间： | 2000-03-14 |
New Method for Synthesis of 4-Substituted Benzamido-2-thioxo-2,4-thiazolidindiones |
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| CHU Chang-Hu,XU Peng-fei,HUI Xin-Ping,ZHANG Zi-yi,LIAO Ren-An,LI Zhi-chun.New Method for Synthesis of 4-Substituted Benzamido-2-thioxo-2,4-thiazolidindiones[J].Chemical Research In Chinese Universities,2001,22(5):768-770. |
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| Authors: | CHU Chang-Hu XU Peng-fei HUI Xin-Ping ZHANG Zi-yi LIAO Ren-An LI Zhi-chun |
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| Institution: | 1. National Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China;
2. State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China |
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| Abstract: | Eight 3-substituted benzamido-2-thioxo-2,4-thiazolidindione derivatives 2a-2h were synthesized and the reaction mechanism was also discussed. The structures of these compounds were confirmed by elemental analyses and spectra data. The preliminary biological test showed that the representative compounds exhibited moderate antifungal and plant growth regulatory activities. |
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| Keywords: | 2-Thioxo-2 4-thiazolidindione Synthesis Mechanism Biological activities |
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