Ortho-substituted aryl monoboronic acids have improved selectivity for d-glucose relative to d-fructose and l-lactate期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Ortho-substituted aryl monoboronic acids have improved selectivity for d-glucose relative to d-fructose and l-lactate

Authors:	J.S. Hansen J.B. ChristensenT.I. Solling P. JakobsenT. Hoeg-Jensen

Affiliation:	^a Department of Chemistry, Universitetsparken 5, DK-2100 Copenhagen, Denmark ^b Novo Nordisk, Novo Nordisk Park D6.1.142, DK-2760 Maaloev, Denmark

Abstract:	Ortho-substituted aryl monoboronic acids have been found to have improved selectivity for d-glucose compared to d-fructose and l-lactate. These findings are supported by computational studies on the B3LYP/6-31G(d) level using Gaussian. This finding is of interest for development of boronate based d-glucose sensors.

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