| 2-芳基-5-(5-苯基-2H-四唑-2-亚甲基)-1,3,4-噁二唑类化合物的研究 |
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| 引用本文： | 冯小明,张自义,孟仟祥,郑国钰. 2-芳基-5-(5-苯基-2H-四唑-2-亚甲基)-1,3,4-噁二唑类化合物的研究[J]. 有机化学, 1990, 0(1) |
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| 作者姓名： | 冯小明 张自义 孟仟祥 郑国钰 |
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| 作者单位： | 西南师范大学化学系，兰州大学化学系，中国科学院地质研究所，兰州大学生物系 重庆 630715，兰州，730000，兰州，730000，兰州，730000 |
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| 摘 要： | 作者曾研究2-芳基-5-(2-苯基-4-喹啉基)-1,3,4-噁二唑类衍生物,并发现它们具有促进小麦发芽生长的功效。Juby和Shan等报道某些四唑类化合物具有消炎性
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| 关 键 词： | 2-芳基-5-(5-苯基-2H-四唑-2-亚甲茎)-1 3 4-噁二唑 MS 生物活性 |
Studies on the 2-Aryl-5-(5-phenyl-2 H-tetrazole-2-methylene)-1, 3, 4-oxadiazoles Derivatives |
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| FENG Xiao-ming,ZHANG Zi-Yi,MENG Qian-Xiang,ZHENG Go-Yu. Studies on the 2-Aryl-5-(5-phenyl-2 H-tetrazole-2-methylene)-1, 3, 4-oxadiazoles Derivatives[J]. Chinese Journal of Organic Chemistry, 1990, 0(1) |
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| Authors: | FENG Xiao-ming ZHANG Zi-Yi MENG Qian-Xiang ZHENG Go-Yu |
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| Affiliation: | FENG Xiao-ming,ZHANG Zi-Yi,MENG Qian-Xiang,ZHENG Go-Yu Department of Chemistry,Southwest Teacher's University,Chongqing 630715 Department of Chemistry,Lanzhou University,Lanzhou 730000 Lanzhou Institute of Geology,Academia Sinica,Lanzhou 730000 Department of Biology,Lanzhou University,Lanzhou 730000 |
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| Abstract: | Cyclization of a series of N-(5-phenyl-2 H-tetrazolc-2-acetyl)-N'-aroylhydrazinc1 under the catalysis of phosphorus oxychloride has been studied. When the N'-substitutinggroups of 1 were 4-IC_6H_4CO, 2-IC_6H_4CO, and 4-CLC_6H_4CO, the cyclization gave only 2,5-bisaryl-1, 3, 4-oxadiazoles 3, while the expected cyclic compounds 2-aryl-5-(5-phenyl-2 H-tetrazole-2-methylene)-1, 3, 4-oxadiazoles 2 was obtained from 1. Preliminary bioassay showed that 2 exhibited a little inhibiting effect on EscherichiaColi and Bacillus Subtilis. |
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| Keywords: | 2-aryl-5-(5-phenyl-2 H-tetrazole-2-methylene)-1 3 4-oxadiazole MS biological activity |
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