| 黄瑞香生物活性二萜的研究 |
| |
| 引用本文： | 王成瑞,安保,李士敏,周炳南.黄瑞香生物活性二萜的研究[J].化学学报,1987,45(10):993-996. |
| |
| 作者姓名： | 王成瑞 安保 李士敏 周炳南 |
| |
| 作者单位： | 中国科学院上海药物研究所 |
| |
| 摘 要： | 从瑞香科植物黄瑞香的根和茎皮的乙醇提取物中分得一新的活性二萜,命名为黄瑞香丙素(1)和两个已知活性二萜,瑞香毒素(2),12-羟基瑞香毒素(3)及已知双香豆素(daphnoretin, 4),根据它们的光谱数据和衍生物数据确定其结构.1,2,3均具有刺激皮肤粘膜的作用.
|
| 关 键 词： | 晶体结构测定 生物活性 质谱法 质子磁共振谱法 二萜 瑞香科 双香豆素 |
The studies on the bioactive diterpenes from daphne giraldii |
| |
| WANG CHENGRUI,AN BAOZHU,LI SHIMIN,ZHOU BINGNAN.The studies on the bioactive diterpenes from daphne giraldii[J].Acta Chimica Sinica,1987,45(10):993-996. |
| |
| Authors: | WANG CHENGRUI AN BAOZHU LI SHIMIN ZHOU BINGNAN |
| |
| Abstract: | From the alcohol extract of the stem and root barks of the Chinese traditional medicinal plant, D. giraldii (Thymelaeaceae), a new bioactive diterpene, daphnegiraldifin (I), C43H60O9, white amorphous powder), was isolated in 0.00093% yield. Besides, two known bioactive diterpenes and a coumarin were also isolated and identified as daphnetoxin, 12-hydroxydaphnetoxin, and daphnoretin. Their structures were elucidated according to UV, IR, mass, and 1H NMR spectra and chem. evidence. I, daphnetoxin, and hydroxydaphnetoxin are skin irritants. |
| |
| Keywords: | CRYSTAL STRUCTURE DETERMINATION BIOLOGICAL ACTIVITY MASS SPECTROGRAPHY PROTON MAGNETIC RESONANCE SPECTROMETRY DITERPENES THYMELAEEACEAE DICOUMAROLUM |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《化学学报》浏览原始摘要信息 |
| 点击此处可从《化学学报》下载免费的PDF全文 |
|
