Di-tert-butyl dicarbonate as an efficient coupling reagent for the immobilization of carboxylic acid moieties |
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Authors: | Marí a de los Angeles Laborde |
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Affiliation: | Instituto de Química Rosario (CONICET—UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, 2000 Rosario, Argentina |
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Abstract: | We describe an efficient methodology for anchoring diverse carboxylic acids to hydroxymethylated resins using di-tert-butyl dicarbonate as coupling reagent. The reaction is equally effective for aromatic and aliphatic acids, and Fmoc-protected amino acids. |
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