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Di-tert-butyl dicarbonate as an efficient coupling reagent for the immobilization of carboxylic acid moieties
Authors:Marí  a de los Angeles Laborde
Affiliation:Instituto de Química Rosario (CONICET—UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, 2000 Rosario, Argentina
Abstract:We describe an efficient methodology for anchoring diverse carboxylic acids to hydroxymethylated resins using di-tert-butyl dicarbonate as coupling reagent. The reaction is equally effective for aromatic and aliphatic acids, and Fmoc-protected amino acids.
Keywords:
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