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5-Phenylpyridazinones-A serendipitous route from coumarins |
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| Authors: | Manjunath D Ghate Lokesh A Shastri Geetha M Kulkarni Chung-Ming Sun |
| Institution: | a Department of Chemistry, Karnatak University, Dharwad 580 003, India b Department of Chemistry, Karnatak Science College, Dharwad 580 003, India c Department of Applied Chemistry, National Chiao-Tung University, Hsinchu 300-10, Taiwan, ROC |
| Abstract: | A new route of the ring transformation has been discovered during the reaction of 4-bromomethylcoumarins with hydrazine hydrate leading to the formation of pharmacologically important pyridazinones in a single step with very high yields. These so obtained pyridazinones have the potential for further functional group interconversions. |
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