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Concerning the phakellin substructure of palau’amine
Authors:Masakazu Nakadai  Patrick G Harran
Institution:Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., Dallas, TX 75390-9038, USA
Abstract:The phakellin (6) subunit of palau’amine (1) has been synthesized and found to be devoid of antibacterial activity, resolving the question of whether 1 is simply an elaborate phakellin in terms of its antimicrobial properties.
Keywords:Natural products  Guanidine  Antimicrobial
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