Concerning the phakellin substructure of palau’amine |
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Authors: | Masakazu Nakadai Patrick G Harran |
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Institution: | Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., Dallas, TX 75390-9038, USA |
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Abstract: | The phakellin (6) subunit of palau’amine (1) has been synthesized and found to be devoid of antibacterial activity, resolving the question of whether 1 is simply an elaborate phakellin in terms of its antimicrobial properties. |
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Keywords: | Natural products Guanidine Antimicrobial |
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