Rapid microwave assisted hydration of internal arylalkynes in the presence of PTSA: an efficient regioselective access to carbonyl compounds |
| |
| Authors: | Gaë lle Le Bras,Jean-Franç ois Peyrat,Jean-Daniel Brion |
| |
| Affiliation: | Laboratoire de Chimie Thérapeutique, BioCIS-CNRS (UMR 8076), Université Paris-Sud, Faculté de Pharmacie, rue J.B. Clément, 92296 Châtenay-Malabry Cedex, France |
| |
| Abstract: | A metal-free procedure for the regioselective hydration of internal arylalkynes under microwave irradiation is described. The reaction promoted by PTSA takes place rapidly in EtOH and regioselectively afforded in good yields various carbonyl compounds 2. |
| |
| Keywords: | Alkynes Microwave assisted hydration PTSA Carbonyl compounds |
| 本文献已被 ScienceDirect 等数据库收录！ |
