Total synthesis of dapiramicin B |
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| Authors: | Hiroyuki Ohno |
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| Affiliation: | Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan |
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| Abstract: | The first total synthesis of dapiramicin B, a nucleoside antibiotic, is described. The characteristic N-glycoside linkage in dapiramicin B was effectively constructed by way of the Pd-catalyzed coupling reaction of a heptopyranosylamine with a bromopyrrolopyrimidine derivative. |
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| Keywords: | Dapiramicin B Nucleoside antibiotic Total synthesis Pd-Catalyzed N-Arylation |
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