Hydroxycinnamic acid clustered by a calixarene platform: radical scavenging and antioxidant activity |
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| Authors: | Grazia ML Consoli |
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| Institution: | Istituto di Chimica Biomolecolare, CNR, Via del Santuario 110, I-95028 Valverde (CT), Italy |
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| Abstract: | Novel hydroxycinnamic acid-calix4]arene hybrids 4 and 5 were synthesized. Their radical scavenging and antioxidant activities were determined by using DPPH radical and AIBN-induced linoleic acid peroxidation test, respectively. Preliminary studies showed that compounds 4 and 5 possess enhanced activity with respect to the corresponding hydroxycinnamic acid and phenetidine derivative. Kinetic solvent effects were taken in account to understand the different antioxidative behaviour of the synthesized compounds. |
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| Keywords: | Calixarene Hydroxycinnamic acids Radical scavenging and antioxidant activity |
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