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Novel synthesis of sterically hindered N-substituted lactams from imides
Authors:Mousumi Sannigrahi  Patrick Pinto  TM Chan  Neng-Yang Shih  F George Njoroge
Institution:Schering Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, United States
Abstract:An efficient and practical synthesis of sterically hindered N-substituted lactams has been developed starting from simple starting materials. The stereochemistry of the synthetically useful N,N acetal intermediate has been established.
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