The true configuration of the benzilosazone isomers |
| |
Authors: | María V Mirífico José A Caram |
| |
Institution: | a Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), Facultad de Ciencias Exactas, Departamento de Química, Universidad Nacional de La Plata. C.C. 16, Suc. 4, (1900) La Plata, Argentina b Fac. de Ingeniería, Universidad Nacional de La Plata, Argentina |
| |
Abstract: | The 1H NMR-based argument previously used to assign configurations to the three stereoisomers of benzilosazone is briefly reviewed. The configuration of the stable isomer is shown to be Z,Z by single crystal X-ray diffraction analysis, instead of E,E as previously reported. This assignment, together with physical measurements and spectroscopic (NMR and UV) data, allows the establishment of the configuration of all isomers. Computational methods are employed to clarify the relation between the configuration of the isomers and their 1H NMR, thus explaining the origin of the previous erroneous assignment. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|