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An isocyanide-based three-component reaction: synthesis of fully substituted N-alkyl-2-triphenylphosphoranylidene glutarimides |
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| Authors: | Ahmad Shaabani Ebrahim Soleimani Ralf-Dieter Hoffmann Rainer Pöttgen |
| Institution: | a Department of Chemistry, Shahid Beheshti University, PO Box 19396-4716, Tehran, Iran b Institut für Anorganische und Analytische Chemie, Universität Münster, Corrensstrasse 30, D-48149 Münster, Germany |
| Abstract: | A three-component condensation reaction between an isocyanide, an electron-deficient acetylenic ester and (ethoxycarbonylmethyl)triphenylphosphonium bromide efficiently provides fully substituted N-alkyl-2-triphenylphosphoranylidene glutarimides in a one-pot reaction without any activation or modification. |
| Keywords: | Glutarimide Piperidine-2 6-dione Isocyanide Multi-component reactions |
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