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Total synthesis of (−)-clavosolide A
Authors:Tushar Kanti Chakraborty  Vakiti Ramkrishna Reddy  Amit Kumar Chattopadhyay
Affiliation:Indian Institute of Chemical Technology, Hyderabad 500 007, India
Abstract:The total synthesis of (−)-clavosolide A is achieved employing a radical-mediated route to build the substituted tetrahydropyran unit, a Yamaguchi reaction to construct the diolide aglycon and the Schmidt method for the final glycosidation step.
Keywords:Clavosolides   Clavosolide A   Epoxide opening   2-Methyl-1,3-diol   Diolide
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