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Copper-catalyzed N-arylation of diazoles with aryl bromides using KF/Al2O3: an improved protocol
Authors:Rahman Hosseinzadeh  Mahmood Tajbakhsh
Affiliation:a Faculty of Basic Science, Mazandaran University, Babolsar, Iran
b Islamic Azad University, Ilam, Iran
Abstract:Copper-catalyzed N-arylation of diazoles can be accomplished using air-stable CuI as a copper source and 1,10-phenanthroline in the presence of KF/Al2O3 as a base. This is a simple and efficient method for the coupling of aryl bromide with diazoles. Different functionalized aryl bromides were coupled with diazoles using this system.
Keywords:Copper-catalyzed   Coupling   N-arylation   Diazoles   Aryl bromide
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