A one-pot method for the synthesis of 2-aminobenzimidazoles and related heterocycles |
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| Authors: | Victor J. Cee Nicholas S. Downing |
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| Affiliation: | Amgen Inc., Chemistry Research and Discovery, One Kendall Square Building 1000, Cambridge, MA 02139, USA |
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| Abstract: | A rapid and efficient one-pot method for the synthesis of 2-aminobenzimidazoles and related heterocycles is described. The reaction is mediated by a polymer-supported carbodiimide, which simplifies product isolation. The scope and limitations of this method are described. |
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| Keywords: | Aminobenzimidazole Cyclodesulfurization Polymer-supported carbodiimide |
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