Synthesis of tritium labeled KRN7000 |
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| Authors: | Martijn DP Risseeuw Hidde L Ploegh |
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| Institution: | Harvard Medical School, Department of Pathology, 77 avenue Louis Pasteur Boston, MA 02115, USA |
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| Abstract: | The synthesis of a multiple tritiated analog of KRN7000 (α-galactosyl ceramide) is described, enabling further studies to quantitate the affinity of KRN7000 for its receptor and to study its pharmacokinetic properties. |
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| Keywords: | Glycolipids Ceramides CD1 ligands Tritiated compounds |
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