Synthesis of 2-substituted benzylidene-6-b-nitrothiazolo[3,2-α]benzimidazol-3(2H)ones as possible anticonvulsants |
| |
Authors: | S P Singh S S Parmar B R Pandey |
| |
Abstract: | Several 2-substituted benzylidene-b-nitrothiazolo3,2-α]benzimidazol-3(2H)ones were prepared by the condensation of 6-nitrothiazolo3,2-α]benzimidazol-3(2H)one with suitable aryl aldehydes as possible anticonvulsants. Amongst these benzimidazoles, two compounds possessed anticonvulsant activity and provided 60% protection against pentylene-tetrazol-induced seizures in mice. J. Heterocyclic Chem., 14, 1093 (1977) |
| |
Keywords: | |
|
|