New steroidal alkaloids from Sarcococca saligna |
| |
| Authors: | Atta-ur-Rahman Feroz Fareeda Zaheer-ul-Haq Nawaz Sarfraz A Khan M Riaz Choudhary M Iqbal |
| |
| Institution: | H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan. |
| |
| Abstract: | Two new steroidal alkaloids, salonine-A (20S)-20-(N,N-dimethylamino)-3beta-(tigloylamino)-5alpha-pregn-14-en-2beta,4beta-diol] (1), and salonine-B (20S)-20-(N,N-dimethylamino)-3beta-methoxy-pregn-5,16-diene] (2), were isolated from the MeOH extract of Sarcococca saligna, along with a known base, alkaloid-C (3). Their structures were elucidated on the basis of spectroscopic methods. All three compounds were found to be cholinesterase inhibitors. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
