Concise synthesis of 3,4-dihydro-1,4-benzoxazines by three-component reactions of acyl chlorides, o-aminophenols and 1,2-dichloroethane |
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| Authors: | Yunyun Liu Xuwen Chen |
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| Institution: | College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, PR China |
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| Abstract: | The Cu(OAc)2-catalyzed three-component reactions of o-aminophenols, acyl chlorides and 1,2-dichloroethane (DCE) have been established for the efficient synthesis of 3,4-dihydro-2H-benzob]1,4]oxazines (3,4-dihydro-1,4-benzoxazines). This method features advantages of the one-pot operation enabling N-acylation, C | |
| Keywords: | Three-component Copper catalysis Selective 3 4-Dihydro-1 4-benzoxazine Corresponding author |
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