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Ru3(CO)12-catalyzed dehydrogenative SiN coupling of indoles with hydrosilanes without additive
Authors:Wenchao Zhai  Bin Li  Baiquan Wang
Institution:1. State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, People''s Republic of China;2. Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300071, People''s Republic of China;3. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, People''s Republic of China
Abstract:An efficient Ru3(CO)12-catalyzed dehydrogenative Si/>N coupling reaction of indoles, pyrrole, and carbazole with hydrosilanes is reported. The reaction does not need any external additive. This catalytic reaction has a wide substrate range, excellent functional group tolerance, and high to excellent reaction efficiency. Gram-scale synthesis demonstrates the practicability of this synthetic method.</td>
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Keywords:Ruthenium carbonyl  Si  N dehydrogenation coupling  Indoles  Hydrosilanes
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