Azolo[5,1-c]-1,2,4-triazines as a new class of antiviral compounds |
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| Authors: | V. L. Rusinov E. N. Ulomskii O. N. Chupakhin V. N. Charushin |
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| Affiliation: | (1) Urals State Technical University, 19 ul. Mira, 620002 Ekaterinburg, Russian Federation;(2) I. Ya. Postovsky Institute of Organic Synthesis, Urals Branch of the Russian Academy of Sciences, 20 ul. S. Kovalevskoi, 620219 Ekaterinburg, Russian Federation |
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| Abstract: | Synthetic methods, reactivity, and the properties of a new class of antiviral compounds, pyrazolo-, imidazo-, 1,2,4-triazolo[5,1-c]-1,2,4-triazinones, tetrazolo[5,1-b]-1,2,4-triazinones, and azoloannulated amino-1,2,4-triazines having structural similarity with biogenic purines and capable of mimicking them in metabolic processes are considered. Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 967–995, May, 2008. |
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| Keywords: | pyrrolo[5,1-c]-1,2,4-triazines pyrazolo[5,1-c]-1,2,4-triazines imidazo[5,1-c]-1,2,4-triazines imidazo[2,1-c]-1,2,4-triazines 1,2,4-triazolo[5,1-c]-1,2,4-triazines tetrazolo[5,1-b]-1,2,4-triazines abnormal nucleosides antiviral compounds |
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