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Synthesis of 6-sulfamoyl-4-oxoquinoline-3-carboxylic acid derivatives as integrase antagonists with anti-HIV activity |
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| Authors: | Zai Gang Luo Cheng Chu Zeng Lei Fu Yang Hong Qiu He Cun Xin Wang Li Ming Hu College of Life Science Bioengineering Beijing University of Technology Beijing China |
| Institution: | College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China |
| Abstract: | A series of novel 6-sulfamoyl-4-oxoquinoline-3-carboxylic acids derivatives have been synthesized and screened for HIV integrase inhibition activity.Their structures were confirmed by ESI-MS,~1H NMR and ~(13)C NMR. |
| Keywords: | Quinoline Integrase Anti-HIV-1 activity |
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