Inhibition of human lipoprotein oxidation by morelloflavone and camboginol from Garcinia dulcis |
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Authors: | Hutadilok-Towatana Nongporn Kongkachuay Suyanee Mahabusarakam Wilawan |
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Affiliation: | Department of Biochemistry, Faculty of Science, Prince of Songkla University, Songkhla, Thailand. nongporn@psu.ac.th |
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Abstract: | A biflavonoids, morelloflavone (1) and a prenyltated xanthone, camboginol (2), isolated from the fruits of Garcinia dulcis (Roxb.) Kurz., exhibited strong antioxidation effects in both Fe2+ -mediated and non-metal induced human low-density lipoprotein (LDL) oxidations. However, a well-known antioxidant, alpha-tocopherol (vitamin E), was found less potent than both compounds based on the same test systems. |
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