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Chiral separations by capillary electromigration techniques in nonaqueous media. II. Enantioselective nonaqueous capillary electrochromatography
Authors:Lämmerhofer Michael
Affiliation:Christian Doppler Laboratory for Molecular Recognition Materials, Institute of Analytical Chemistry, University of Vienna, Währingerstrasse 38, A-1090 Vienna, Austria
Abstract:A review on the advantages, peculiarities, and the potential of enantioselective capillary electrochromatography (CEC) in nonaqueous media is presented. Some fundamentals on CEC with particular focus on enantioselective CEC are discussed. The strategies, concepts, preferentially utilized chiral selectors and column technologies that have been utilized to succeed in highly efficient enantiomer separations by nonaqueous CEC are described thoroughly.
Keywords:Chiral separation  Capillary electromigration technique  Nonaqueous media  Separation mechanism  Chiral recognition  Solvent effects  Chiral selector  Chiral stationary phase  Monolithic column  Packed column  Polysaccharides  Cyclodextrin  Macrocyclic antibiotics  Chiral ion-exchangers
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