A novel and green synthesis of kojic acid derivatives in ionic liquid [bmim]BF4 |
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| Authors: | Yuling Li Qiushi JiangKai Wang Baixiang DuXiangshan Wang |
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| Institution: | School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou 221116, China |
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| Abstract: | A series of 3-(3-hydroxy-6-methyl-4-oxo-4H-pyran-2-yl)-3-phenylpropanamide derivatives were synthesized efficiently by one-pot condensation of aromatic aldehydes, meldrum’s acid, allomaltol, and ammonium acetate in ionic liquid bmim]BF4. The novel synthesis method offers the advantage of operational simplicity, mild reaction conditions, short reaction time, higher yields, and environmental friendliness. |
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| Keywords: | Kojic acid derivatives Multi-component reactions Ammonium acetate Ionic liquid |
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