Copper-catalyzed cyanation of aryl iodide with the combined cyanide source of urea and DMSO |
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| Authors: | Kui Zheng Bin LiuShuyou Chen Fan Chen |
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| Institution: | College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China |
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| Abstract: | A simple copper-catalyzed cyanation of aryl iodide with the combination of urea and dimethyl sulfoxide as a cyanide source is achieved, providing nitriles in moderate to good yields. This new approach represents an exceedingly practical and safe method for the synthesis of aryl nitriles. |
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| Keywords: | Copper-catalyzed Cyanation Aryl iodide Nitriles |
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