|
|||||
|
|
Chiral initiator-induces self-disproportionation of enantiomers via achiral chromatography: application to enantiomer separation of racemate |
|
| Authors: | Kaori Tateishi Shiori Tsukagoshi Tsuyoshi Nakamura Shotaro Watanabe Vadim A. Soloshonok Osamu Kitagawa |
| Affiliation: | 1. Department of Applied Chemistry, Shibaura Institute of Technology, 3-7-5 Toyosu, Kohto-ku, Tokyo 135-8548, Japan;2. TAIHO Pharmaceutical Co., Ltd., 200-22, Motohara, Kamikawa-machi, Kodama-gun, Saitama 367-0241, Japan;3. Department of Organic Chemistry I, University of the Basque Country UPV/EHU, 20018 San Sebastián, Spain;4. IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain |
| Abstract: | We report here the theoretical design and proof of principle of the first example of a conceptually new approach for the preparation of enantiomerically pure compounds from the racemates by chiral initiator-induced Self-Disproportionation of Enantiomers (SDE) via achiral chromatography. |
| Keywords: | Enantiomers Disproportionation Optical resolution Chromatography Association |
| 本文献已被 ScienceDirect 等数据库收录！ | |