Click chemistry for the synthesis of 5-substituted 1H-tetrazoles from boron-azides and nitriles |
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Authors: | Yue-Wei Yao Yi Zhou Bao-Ping Lin Cheng Yao |
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Affiliation: | 1. School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China;2. Department of Applied Chemistry, College of Science, Nanjing University of Technology, Nanjing 211816, China |
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Abstract: | A novel and metal free catalysis of synthesizing 5-substituted 1H-tetrazoles through 1,3-dipolar cycloaddition of boron-azides and nitriles is reported with broad substrate scope and excellent yields. |
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Keywords: | Click chemistry Tetrazole Boron-azide Nitrile 1,3-Dipolar cycloaddition |
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