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Click chemistry for the synthesis of 5-substituted 1H-tetrazoles from boron-azides and nitriles
Authors:Yue-Wei Yao  Yi Zhou  Bao-Ping Lin  Cheng Yao
Institution:1. School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China;2. Department of Applied Chemistry, College of Science, Nanjing University of Technology, Nanjing 211816, China
Abstract:A novel and metal free catalysis of synthesizing 5-substituted 1H-tetrazoles through 1,3-dipolar cycloaddition of boron-azides and nitriles is reported with broad substrate scope and excellent yields.
Keywords:Click chemistry  Tetrazole  Boron-azide  Nitrile  1  3-Dipolar cycloaddition
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