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Fluorous-assisted synthesis of (E)-5-[3-Aminoallyl]-uridine-5′-triphosphate
Authors:Anilkumar R Kore  Bo YangBalasubramanian Srinivasan
Institution:Life Technologies Corporation, Bioorganic Chemistry Division, 2130 Woodward Street, Austin, TX 78744-1832, USA
Abstract:We describe an efficient method for the synthesis of (E)-5-3-Aminoallyl]-uridine-5′-triphosphate, AA-UTP that combines the advantage of one-pot triphosphate formation and fluorous solid-phase extraction.
Keywords:Nucleoside triphosphates  One-pot synthesis  Fluorous separation  Phosphorylation
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