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Formation of tryptanthrin compounds upon Oxone-induced dimerization of indole-3-carbaldehydes
Authors:Amber C. Nelson  Emily S. KalinowskiTaylor L. Jacobson  Peter Grundt
Affiliation:Department of Chemistry & Biochemistry, University of Minnesota Duluth, 1039 University Drive, Duluth, MN 55812, United States
Abstract:Tryptanthrin is a natural product with numerous important pharmacological properties. Tryptanthrin and its analogs are commonly prepared by condensation of isatoic anhydride and isatin. In this Letter we investigate the formation of tryptanthrin derivatives upon Oxone-induced oxidative dimerization of indole-3-carbaldehydes.
Keywords:Natural product synthesis   Tryptanthrin   Oxidation
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