Formation of tryptanthrin compounds upon Oxone-induced dimerization of indole-3-carbaldehydes |
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Authors: | Amber C. Nelson Emily S. KalinowskiTaylor L. Jacobson Peter Grundt |
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Affiliation: | Department of Chemistry & Biochemistry, University of Minnesota Duluth, 1039 University Drive, Duluth, MN 55812, United States |
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Abstract: | Tryptanthrin is a natural product with numerous important pharmacological properties. Tryptanthrin and its analogs are commonly prepared by condensation of isatoic anhydride and isatin. In this Letter we investigate the formation of tryptanthrin derivatives upon Oxone-induced oxidative dimerization of indole-3-carbaldehydes. |
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Keywords: | Natural product synthesis Tryptanthrin Oxidation |
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