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Palladium-catalyzed asymmetric hydrogenation of dibenzo[b,f][1,4]thiazepines activated by Brønsted acid
Authors:Jinzhu Wang
Affiliation:Department of Chemistry, Jiaozuo Zhigong Medical College, Jiaozuo, Henan 454000, PR China
Abstract:An efficient and facile route to chiral dihydrodibenzothiazepines has been successfully developed via palladium-catalyzed asymmetric hydrogenation of the dibenzothiazepines with Brønsted acid as activator with up to 94% ee.
Keywords:Dihydrodibenzothiazepines   Palladium   Asymmetric hydrogenation
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