An efficient diastereoselective route to differentially protected anti-4-amino-1-alken-3-ols |
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| Authors: | Lombardo Marco Mosconi Elisa Pasi Filippo Petrini Marino Trombini Claudio |
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| Institution: | Dipartimento di Chimica G. Ciamician, Università di Bologna, via Selmi 2, I-40126 Bologna, Italy. marco.lombardo@unibo.it |
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| Abstract: | Zinc-promoted hydroxyallylation of alpha-amidoalkyl arylsulfones 4 using 3-bromo-propenyl methyl carbonate 5 proceeds smoothly in DMF at room temperature to afford high yields of differentially protected anti-1,2-amino alcohols 6. |
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