Spectroscopic Studies and Crystal Structure of 1-(Morpholino (Phenyl) Methyl) Pyrrolidine-2,5-Dione

Abstract  

A new mannich base 1-(morpholino(phenyl)methyl)pyrrolidine-2,5-dione formed by the direct condensation of morpholine, succinimide and benzaldehyde has been synthesized. The structure of this mannich base has been elucidated on the basis of micro elemental analysis, IR, ¹H NMR, ¹³C NMR, UV–Visible Techniques and Mass. The crystal structure of the title compound C₁₅ H₁₈ N₂ O₃ was determined. It crystallizes in the triclinic system, space group P − 1, with a = 8.8122(13) ?, b = 9.2794(14) ?, c = 9.814 (3) ?, α = 107.154(9)°, β = 97.936(9)°, γ = 110.197(7)°,V = 693.4(2) ?³, D _x  = 1.314 Mg/m³. The structure was solved by the full-matrix least squares on F² and had a refined R value of 0.0486 for 8567 observed reflections. The six membered heterocyclic ring of the morpholino moiety adopts a chair conformation. The crystal structure is stabilized by weak intermolecular C–H···O interactions that link the molecules into inversion dimers.