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New method for the synthesis of 2-phenylproline and its derivatives
Authors:A. O. Martirosyan  S. P. Gasparyan  V. E. Oganesyan  Sh. L. Mndzhoyan  M. V. Aleksanyan  M. N. Nikishchenko  G. Sh. Babayan
Abstract:A new method has been developed for the synthesis of 2-phenylproline and its derivatives by intramolecular cyclization of the corresponding derivatives of N-(3-chloro-or 1-oxo-3-chloropropyl)-agr-phenylglycine under phase transfer catalysis conditions.A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia, 375014 Yerevan, Armenia; e-mail: rafael@msrc.am. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 488–492, April, 2000.
Keywords:amino acids  phenylproline  intramolecular cyclization  phase-transfer catalysis
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