SOLID PHASE SYNTHESIS OF ISOXAZOLINES |
| |
| Authors: | SUN Weimin LUO Juntao HUANG Wenqiang |
| |
| Institution: | State Key Laboratory of Functional Polymer Material for Adsorption and Separation, Institute of Polymer Chemistry, Nankai University, Tianjin 300071, China |
| |
| Abstract: | The solid-phase synthesis of isoxazolines on 2-polystyrylsulfonamidoethanol resin isreported. 2-Polystyrylsuifonamidoethanol resin 1 was reacted with acryloyl chloride to afford2-polystyrylsulfonylamidoethyl acrylate resin 2, which was further reacted with brominatedaldoximes by 3+2] cycioaddition to give isoxazoline resin 4. Resin 4 was treated with aqueous 6mol/L HCI solution to obtain isoxazolines in good yield and purity. |
| |
| Keywords: | Solid phase synthesis 2-Polystyrylsulfonamidoethanol lsoxazoline |
| 本文献已被 维普 万方数据 等数据库收录！ |
