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Synchronization of low-frequency oscillations in the cardiovascular system: Application to medical diagnostics and treatment
Authors:VI Ponomarenko  MD Prokhorov  AS Karavaev  AR Kiselev  VI Gridnev  BP Bezruchko
Institution:1. Saratov Branch of the Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia
2. Department of Nano- and Biomedical Technologies, Saratov State University, Saratov, Russia
3. Saratov Research Institute of Cardiology, Saratov, Russia
Abstract:We investigate synchronization between the low-frequency oscillations of heart rate and blood pressure having in humans a basic frequency close to 0.1?Hz. A quantitative estimation of this synchronization based on calculation of relative time of phase synchronization of oscillations is proposed. We show that assessment of synchronization between the considered oscillations can be useful for selecting an optimal dose of beta-blocker treatment in patients after acute myocardial infarction. It is found out that low value of synchronization between the low-frequency rhythms in heart rate and blood pressure at the first week after acute myocardial infarction is a sensitive marker of high risk of mortality during the subsequent 5 years.
Keywords:
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