1-Nucleosides of 5-substituted 4-chloro-1,2,3-triazoles |
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| Authors: | I. D. Shingarova I. V. Yartseva M. P. Nemeryuk A. L. Sedov T. S. Safonova G. A. Osipov Yu. Yu. Volodin M. N. Preobrazhenskaya |
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| Affiliation: | (1) All-Union Oncologic Science Center, Academy of Medical Sciences of the USSR, 115478 Moscow;(2) S. Ordzhonikidze All-Union Pharmaceutical Chemistry Scientific-Research Institute, 119021 Moscow |
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| Abstract: | 1-Nucleosides of 5-substituted 4-chloro-1,2,3-triazoles were produced by glycosylation of the corresponding triazoles by the method of fusion with tetra-0-acyl-D-ribofuranose in the presence of bis-p-nitrophenyl phosphate. The structure of the compounds obtained and their conformational peculiarities were studied by the methods of mass spectrometry and NMR spectroscopy.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1556–1564, November, 1984. |
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