The use of bifunctional catalyst systems in the asymmetric addition of alkynylzinc to aldehydes |
| |
| Institution: | 1. College of Water Resources and Architectural Engineering, Northwest A&F University, Yangling 712100, China;2. State Key Laboratory of Structural Analysis for Industrial Equipment, Dalian University of Technology, Dalian 116024, China;3. School of Port and Transportation Engineering, Zhejiang Ocean University, Zhoushan 316022, China;4. Centre for Innovative Structures and Materials, School of Engineering, RMIT University, Melbourne, VIC 3001, Australia |
| |
| Abstract: | The bifunctional ligand 2a showed a more enhanced reactivity than that of the corresponding amino alcohol ligand in the asymmetric addition of alkynylzinc to benzaldehyde. The bifunctional ligand 2a can catalyze the addition of phenylacetylene to various types of aldehydes including aromatic aldehydes, aliphatic aldehydes, and α,β-unsaturated aldehydes with high enantioselectivity (81–98% ee). The conditions of this catalytic process are both mild and simple. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
