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Enantioselective transport of amino acids as their potassium and sodium salts by optically active diaza-18-crown-6 ethers having arene sidearms |
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| Institution: | 1. Center for Energy and Environmental Research, National Tsing Hua University, Hsinchu 30013, Taiwan;2. Department of Chemical and Materials Engineering, Tunghai University, Taichung 40704, Taiwan;1. Global Discovery Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA;2. Infectious Disease Area, Novartis Institutes for Biomedical Research, 100 Technology Square, Cambridge, MA 02139, USA |
| Abstract: | The enantioselective transport of amino acids as their sodium and potassium salts has been investigated by optically active diaza crown ethers. The reversed enantioselectivity of chiral crown ether 1 was observed. |
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