TEMPO-catalyzed decarboxylation reactions for the synthesis of 1,2-unsubstituted indolizines |
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| Authors: | Yuxuan Zhang Wenhui Wang Jinwei Sun Yun Liu |
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| Affiliation: | School of Chemistry and Material Science, Jiangsu Normal University, Xuzhou, China |
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| Abstract: | An efficient synthesis of 1,2-unsubstituted indolizines was developed via 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO)–catalyzed decarboxylation reaction. A series of target products were successfully prepared with the tolerance of a variety of functional groups. This protocol features advantages such as easily available substrates, broad substituent scope, and eco-friendly conditions. |
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